senna + gastrofin; sodium picosulfate + magnesium citrate

This entry refers to a combination of two multi-agent bowel preparation regimens, each used for gastrointestinal cleansing prior to procedures such as colonoscopy. The first regimen, "senna + gastrofin," combines senna (a stimulant laxative derived from Senna alexandrina) with Gastrofin (likely referring to Gastrografin, a contrast agent containing diatrizoate meglumine and diatrizoate sodium). Senna increases intestinal motility and fluid secretion in the colon, promoting bowel evacuation[1][5]. Gastrografin is an oral or rectal radiopaque contrast medium that also has osmotic laxative properties[3]. The second regimen, "sodium picosulfate + magnesium citrate," is a well-established oral bowel cleansing agent. Sodium picosulfate acts as a stimulant laxative by increasing peristalsis in the colon, while magnesium citrate acts as an osmotic laxative by drawing water into the intestines[6][8][10]. This combination induces watery diarrhea for effective colonic cleansing before diagnostic procedures. Both regimens are used primarily for short-term bowel preparation and not recommended for chronic use due to risks of electrolyte imbalance.

Brand names

ClenpiqPrepopikCitraFleetPicolax

Other names

sennosides + gastrografin; sodium picosulfate/magnesium citrate