sepetaprost + timolol

Sepetaprost + timolol is a fixed-dose combination therapy under development for the treatment of glaucoma and ocular hypertension. Sepetaprost (STN1012600) is a prostaglandin derivative that acts as a dual agonist at the Prostaglandin F receptor and Prostaglandin E receptor 3 subtype, leading to reduced intraocular pressure. Timolol is a non-selective beta-adrenergic blocker that decreases aqueous humor production in the eye by blocking beta-adrenergic receptors, further lowering intraocular pressure. The combination leverages two complementary mechanisms to enhance efficacy in reducing intraocular pressure for patients with open-angle glaucoma or ocular hypertension[5][6][8].

Other names

sepetaprost + timolol maleate