Drug intelligence / Profile preview

sericin + turmeric

Development stage
Preclinical
Modality
Recombinant Proteins and Enzymes
Administration
Topical, Oral
01

Overview

Sericin + turmeric is a topical combination therapy being investigated for the treatment of psoriasis. [9] It combines sericin, a protein derived from silk, with turmeric, a plant extract. Sericin possesses anti-inflammatory, antioxidant, and moisturizing properties, and has been shown to promote collagen production. [2, 9] Turmeric and its active component, curcumin, are known for their potent anti-inflammatory and antioxidant effects, which are mediated in part by the inhibition of inflammatory cytokines like TNF-α, IL-6, and IL-17. [1, 3] In a clinical trial, a cream containing this combination is applied to psoriatic lesions to reduce severity, inflammation, and improve skin barrier function. [3, 9]

02

Targets

IL-17A (Interleukin-17A)IL-6 (Interleukin 6)PHKA2 (Phosphorylase Kinase)TNFA (Tumor necrosis factor alpha (soluble))

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