Drug intelligence / Profile preview

SF Easyhaler + charcoal

Development stage
Phase 1
Lead developer
Orion
Modality
Small Molecules
Administration
Inhalation, Oral
01

Overview

Salmeterol/Fluticasone Easyhaler (SF Easyhaler) is a combination dry powder inhaler developed by Orion Corporation for the treatment of asthma and chronic obstructive pulmonary disease (COPD). It delivers a fixed-dose combination of salmeterol xinafoate, a long-acting beta-2 adrenoceptor agonist (LABA) that provides sustained bronchodilation, and fluticasone propionate, a synthetic corticosteroid with potent anti-inflammatory action. In clinical pharmacology, "SF Easyhaler + charcoal" refers to the administration of the inhaler alongside activated charcoal. This protocol is specifically used in pharmacokinetic studies to block the gastrointestinal absorption of the swallowed portion of the inhaled dose, thereby allowing researchers to isolate and assess the pulmonary deposition and absorption of the active ingredients.

Brand names
Safumix Easyhaler
Other names
Salmeterol/Fluticasone Easyhaler + charcoalSalmeterol/Fluticasone Propionate Easyhaler
02

Targets

ADRB2 (β2)GR (Glucocorticoid receptor)

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