Drug intelligence / Profile preview

shea butter + ceramide

Development stage
Unknown
Lead developer
TIMEBIO
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Shea butter + ceramide is a topical combination product formulated primarily as a skin moisturizer and barrier repair agent. The formulation typically contains Butyrospermum parkii (shea butter), which acts as an emollient to soften and soothe dry or compromised skin, and Ceramide NP, a lipid molecule that helps restore the skin’s natural barrier function by replenishing essential lipids. This combination is used in over-the-counter creams for conditions such as eczema, atopic dermatitis, dry skin, and other forms of dermatitis. The mechanism of action involves both occlusive moisturizing from shea butter and reinforcement of the stratum corneum lipid matrix by ceramides to reduce transepidermal water loss and improve overall skin hydration[1][2][4][6]. These products are not FDA-approved drugs but are widely marketed for dermatological use.

Brand names
Ato Standard Premium Mildcream
Other names
shea butter and ceramide creamshea butter + ceramide NP creambutyrospermum parkii (shea butter) + ceramide NP
02

Targets

Stratum corneum lipid matrix

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