Drug intelligence / Profile preview

shepherd's purse

Development stage
Phase 4
Administration
Oral, Sublingual, Topical
01

Overview

Shepherd's purse (Capsella bursa-pastoris) is a medicinal plant in the Brassicaceae family recognized for its hemostatic, anti-inflammatory, and antimicrobial properties. It contains various bioactive compounds, including flavonoids, sulfur glycosides (bursapastoris A-B), and the antimicrobial peptide Shepherin I. Clinical research has evaluated its efficacy in herbal vagitories for treating non-specific vaginitis, where it demonstrated improvements in both subjective and objective symptoms. Additionally, it is studied for its potential to control severe hemorrhagic wounds through incorporation into hydrogel-based dressings and for its ability to mitigate liver injury by regulating glucolipid metabolism and the NF-κB signaling pathway. Caution is advised regarding its use alongside anticoagulants like warfarin due to potential drug-herb interactions that may increase bleeding risks.

Other names
Capsella bursa-pastorisshepherd's purse herbWESPCapsella apetala
02

Targets

NF-κB

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