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sildenafil + losartan
- Development stage
- Preclinical
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination of sildenafil, a phosphodiesterase-5 (PDE5) inhibitor used for erectile dysfunction, and losartan, an angiotensin II receptor blocker (ARB) used for hypertension. This combination may have additive effects on lowering blood pressure and potentially beneficial effects on erectile function, particularly in diabetic patients.
02
Targets
AGTR1 (Angiotensin II Type-1 receptor)PDE5 (Phosphodiesterase 5A)
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