Drug intelligence / Profile preview

silver diamine fluoride + glass ionomer

Development stage
Unknown
Lead developer
Cairo University
Modality
Small Molecules
Administration
Topical
01

Overview

Silver diamine fluoride + glass ionomer is a combination therapy utilized in restorative dentistry for the management of deep dental caries, particularly for indirect pulp capping in young permanent teeth. Silver diamine fluoride (SDF) is a topical medicament that acts as a potent antimicrobial and caries-arresting agent; its silver ions disrupt bacterial DNA and proteins, while its fluoride ions promote the remineralization of tooth structure to form acid-resistant fluorapatite. Glass ionomer (GI) is a restorative material that chemically bonds to the tooth structure, providing a marginal seal and a sustained release of fluoride to further aid in remineralization. This specific combination is being evaluated by Cairo University in a randomized pilot study to assess its clinical success and impact on postoperative pain in asymptomatic teeth with deep caries and open apices following minimal caries removal.

Other names
SDF + GISilver Diamine Fluoride and Glass Ionomer
02

Targets

Neuraminidase

Beyond the preview

Go deeper on silver diamine fluoride + glass ionomer.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on silver diamine fluoride + glass ionomer.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call