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Sinol M Allergy & Sinus Relief
- Development stage
- Unknown
- Lead developer
- Sinol
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Intranasal
01
Overview
Sinol M Allergy & Sinus Relief (also marketed as Sinol-M Fast Allergy and Sinus Relief) is an over-the-counter (OTC) homeopathic nasal spray developed by Sinol USA. The primary active ingredient is capsicum (capsaicin), a natural compound derived from pepper plants that acts as a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) channel. By stimulating and subsequently desensitizing TRPV1-expressing sensory neurons in the nasal mucosa, the spray helps to relieve nasal congestion, sinus pressure, allergic rhinitis, and sinus headaches. It is formulated with other natural inactive ingredients, including aloe vera, eucalyptol, rosemary extract, sea salt, and vitamin C, to soothe and moisturize nasal passages.
- Brand names
- Sinol M Allergy & Sinus ReliefSinol-MSinol-M All-Natural Allergy/Sinus Nasal SpraySinol-M Fast Allergy and Sinus ReliefSinolM Fast Allergy and Sinus Relief
- Other names
- capsaicin nasal spraycapsicum nasal spray
02
Targets
CGRP (Calcitonin gene-related peptide)SP (Substance P)TRPM8 (Transient receptor potential cation channel subfamily M member 8)TRPV1 (Transient receptor potential cation channel subfamily V member 1)
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