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sintilimab + docetaxel

Development stage: Unknown
Lead developer: Innovent Biologics
Modality: Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration: Intravenous

Overview

Sintilimab + docetaxel is a combination therapy consisting of sintilimab, a fully human IgG4 monoclonal antibody targeting PD-1 (programmed cell death protein 1), and docetaxel, a taxane-based chemotherapeutic agent. This combination has been investigated primarily as a second-line treatment for patients with advanced non-small cell lung cancer (NSCLC) who have progressed on first-line platinum-based chemotherapy, as well as for extensive-stage small cell lung cancer (ES-SCLC).

Other names: SYS6090 plus docetaxelSYS-6090 plus docetaxelSYS 6090 plus docetaxelSintilimab + docetaxel

Targets

TUBB (Tubulin (alpha and beta subunits))PDCD1 (Programmed cell death protein 1 receptor)

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