Drug intelligence / Profile preview

sitagliptin + metformin (Genix Pharma)

Development stage
Unknown
Lead developer
Genix Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Gvia-M is a branded generic combination of **sitagliptin** and **metformin hydrochloride**, developed and marketed by **Genix Pharma**. It is indicated for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycemic control. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances the body's natural ability to lower high blood sugar by increasing the levels of active incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Metformin is a biguanide that reduces the amount of glucose produced by the liver and improves the body's response to insulin. The combination provides complementary mechanisms of action to manage blood glucose levels more effectively than either agent alone.

Brand names
Gvia-M
Other names
Sitagliptin/Metformin
02

Targets

ND1 (Mitochondrial electron transport chain complex I)DPP-4 (Dipeptidyl Peptidase-IV)

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