sodium acetate + potassium + magnesium + calcium + glucose

Sodium acetate + potassium + magnesium + calcium + glucose is a balanced crystalloid intravenous infusion solution developed primarily by Otsuka Pharmaceutical Factory (marketed under brand names such as Physio 140 and Physio 35) and manufactured by various companies including Jiangsu Hengrui Pharmaceuticals (under the brand name Lejia). It is indicated for the replenishment of extracellular fluid, maintenance of electrolyte balance, and correction of metabolic acidosis in patients who cannot tolerate oral intake or have experienced fluid loss due to surgery, trauma, or dehydration. The solution contains essential physiological electrolytes—sodium, potassium, magnesium, calcium, and chloride—in concentrations that closely mimic human plasma. Sodium acetate is included as an alkalinizing agent and bicarbonate precursor; unlike lactate, acetate is metabolized rapidly in peripheral tissues (such as skeletal muscle) rather than solely in the liver, making it safer for patients with hepatic impairment. The addition of glucose (typically 1% to 10%) provides an immediate source of metabolic energy, helping to suppress the catabolism of body fat and proteins while minimizing the risk of perioperative hypoglycemia.

Brand names

Gluaceto 35Gluaceto35Gluaceto-35LejiaLipushuPhysio 140Physio140Physio-140Physio 35Physio35Physio-35TaipilaiYishunze

Other names

compound electrolyte sodium acetate glucose injectionmultiple electrolytes sodium acetate and dextrose injectionmultiple electrolytes sodium acetate and glucose injectionsodium acetate glucose compound electrolyte injectionsodium potassium magnesium calcium and glucose injectionsodium potassium magnesium calcium glucose injection