sodium acetate + sodium gluconate + sodium chloride + potassium chloride + magnesium chloride

Sodium acetate + sodium gluconate + sodium chloride + potassium chloride + magnesium chloride is a **balanced isotonic crystalloid intravenous electrolyte solution** used for fluid and electrolyte replacement and as an **alkalinizing agent**. Marketed in the US under brands including **Plasma-Lyte A** and **Normosol-R**, it contains sodium, potassium, magnesium, chloride, acetate, and gluconate in concentrations designed to approximate extracellular fluid composition; official labels describe about **140 mEq/L sodium, 5 mEq/L potassium, 3 mEq/L magnesium, 98 mEq/L chloride, 27 mEq/L acetate, and 23 mEq/L gluconate**, with osmolarity around **294 to 295 mOsm/L**. Acetate and gluconate function as bicarbonate precursors after metabolism, supporting acid-base balance rather than acting through a discrete receptor target. It is administered intravenously as a source of water and electrolytes in dehydration and electrolyte disturbances, and related formulations of the same electrolyte composition are also labeled for irrigation, rinsing, and washing. Public labels identify Baxter and Pfizer as major current marketers/manufacturers of this exact electrolyte combination. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6ec9e61c-2c26-402f-8604-f446b2e34058))

Brand names

Plasma-Lyte ANormosol-R

Other names

multiple electrolytes injection type 1multiple electrolytes injection type 1 uspmultiple electrolytes injection type 1 usp pH 7.4multiple electrolytes injection type 1 usp pH 5.5plasma-lyte 148plasma-lyte148plasma-lyte-148physiolyte