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sodium chloride + dextrose monohydrate + magnesium chloride + sodium lactate + calcium
- Development stage
- Approved
- Lead developer
- Fresenius Medical Care
- Modality
- Small Molecules
- Administration
- Intraperitoneal
01
Overview
A sterile **peritoneal dialysis solution** containing dextrose monohydrate, sodium chloride, sodium lactate, magnesium chloride, and calcium as electrolyte and osmotic components. This combination product is marketed as **Delflex** and has been developed and manufactured by **Fresenius Medical Care** for **intraperitoneal** administration in patients with chronic kidney failure and acute renal failure who require peritoneal dialysis when nondialytic medical therapy is inadequate. Dextrose monohydrate functions as the osmotic agent that promotes ultrafiltration across the peritoneal membrane, while sodium, calcium, magnesium, chloride, and lactate help maintain electrolyte and buffer balance during dialysis. The functional biological interface is the **peritoneal membrane**, which serves as the dialysis filter rather than a conventional receptor or enzyme target.
- Brand names
- Delflex
- Other names
- dextrose monohydrate + sodium chloride + sodium lactate + calcium chloride + magnesium chloridesodium chloride + dextrose monohydrate + magnesium chloride + sodium lactate + calciumperitoneal dialysis solution
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