Drug intelligence / Profile preview

sodium chloride + dextrose monohydrate + sodium lactate + calcium chloride + potassium chloride

Development stage
Approved
Lead developer
ICU Medical
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

Sodium chloride + dextrose monohydrate + sodium lactate + calcium chloride + potassium chloride is a fixed-composition **parenteral crystalloid and carbohydrate solution** marketed as Lactated Ringer's and 5% Dextrose Injection. It is an intravenous combination product containing sodium, potassium, calcium, chloride, lactate, and dextrose, used for **fluid and electrolyte replacement**, **alkalinization**, and as a **source of water, electrolytes, and calories** in adults and pediatric patients. Its pharmacologic effect is not mediated through a single receptor target; instead, it works by directly restoring extracellular fluid volume and physiologic ions while providing modest caloric support from dextrose and metabolizable lactate. The product is a hypertonic multi-electrolyte injection solution and has been manufactured commercially by ICU Medical.

Brand names
Lactated Ringer's and 5% Dextrose InjectionLactated Ringer's and Dextrose InjectionLactated Ringer's and Dextrose 5% Injection
Other names
sodium chloride + dextrose monohydrate + sodium lactate + calcium chloride + potassium chloridelactated ringer's and dextroselactated ringer's and 5% dextrosedextrose in lactated ringer'sD5LRD-5LRD 5LRLactated Ringer's and Dextrose Injection USPLactated Ringer's and 5% Dextrose Injection USP

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