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sodium dihydrogen phosphate + disodium hydrogen phosphate
- Development stage
- Unknown
- Lead developer
- Union Hospital of Huazhong University of Science and Technology
- Modality
- Small Molecules
- Administration
- Oral, Nasogastric
01
Overview
Sodium dihydrogen phosphate + disodium hydrogen phosphate is an enteral electrolyte replacement therapy consisting of a combination of two inorganic phosphate salts. It is being evaluated by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology for the treatment of varying degrees of hypophosphatemia, particularly in critically ill patients. The mechanism of action involves direct supplementation of inorganic phosphorus to restore normal serum phosphorus levels, which is essential for cellular energy metabolism (ATP production), bone mineralization, and maintaining the structural integrity of cell membranes. In the clinical trial context, it is administered as granules via oral or nasogastric routes, with dosing stratified by the severity of the phosphorus deficiency.
- Brand names
- Phosribbon
- Other names
- Sodium Dihydrogen Phosphate and Disodium Hydrogen Phosphate GranulesEnteral Phosphate Supplementation
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