Drug intelligence / Profile preview

sodium fluoride + calcium fluoride

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Sodium fluoride + calcium fluoride is a combination of two inorganic fluorides used primarily for dental health. Both compounds act as sources of fluoride ions, which help prevent dental caries (tooth decay) by strengthening tooth enamel and making it more resistant to acid attacks from bacteria. Sodium fluoride is commonly used in oral supplements, toothpaste, and professional dental treatments to inhibit bacterial metabolism and promote remineralization of enamel[1][2][5]. Calcium fluoride also contributes to the remineralization process by delivering additional calcium and forming a protective barrier on teeth, further reducing the risk of cavities[6]. The combination may be found in certain oral care products or supplements aimed at maximizing anti-cavity effects through both systemic (ingested) and topical (applied) mechanisms.

02

Targets

ATP2A2 (Sarco/endoplasmic reticulum calcium ATPase isoform 2a)

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