sodium fluoride + silica

Sodium fluoride + silica is a combination formulation used in oral hygiene products, specifically toothpaste, developed by GSK for the maintenance of gingival health and the prevention of gingivitis. Sodium fluoride acts as a cariostatic and antibacterial agent by enhancing the remineralization of tooth enamel and inhibiting the metabolism of plaque-forming bacteria through the inhibition of the enzyme enolase. Silica serves as a mild abrasive to mechanically remove dental plaque and surface stains. This specific formulation was evaluated as a comparator in clinical trials investigating experimental anti-gingivitis agents, such as those containing isopropylmethylphenol. The combination is intended to maintain optimum gingival health following professional dental cleaning.

Other names

NaF/Silica toothpasteFluoride and Silica toothpastesodium fluoride and silica