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**Sodium fluoride + sodium bicarbonate** is a combination of two inorganic compounds often used as active ingredients in dentifrices (toothpastes). Sodium fluoride acts as an anti-caries agent by promoting remineralization of tooth enamel and inhibiting the demineralization process, as well as inhibiting bacterial enzymes that contribute to caries formation. Sodium bicarbonate functions primarily as a buffering and cleaning agent, neutralizing plaque acids and raising oral pH, thereby aiding in the reduction of dental plaque and improving gum health. These effects are complementary, with sodium fluoride strengthening enamel and sodium bicarbonate facilitating plaque removal and maintaining a neutral oral environment by acting as a mild abrasive and alkaline agent[2][3][4][6][8].
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