Drug intelligence / Profile preview

sodium hyaluronate + corticosteroid

Development stage
Unknown
Lead developer
MDM Healthcare
Modality
Small Molecules
Administration
Intraarticular
01

Overview

ActaVisc + corticosteroid refers to the combination of the sodium hyaluronate brand ActaVisc with a corticosteroid agent, typically used for the management of osteoarthritis pain. Sodium hyaluronate is a high-molecular-weight polysaccharide that serves as a viscoelastic supplement to synovial fluid, enhancing joint lubrication and shock absorption. The addition of a corticosteroid (such as triamcinolone or methylprednisolone) provides potent anti-inflammatory action by binding to glucocorticoid receptors, leading to a reduction in the production of inflammatory cytokines and prostaglandins. This combination is designed to provide rapid symptomatic relief through the steroid while the hyaluronate provides sustained mechanical and biological support to the joint environment. While sodium hyaluronate is often regulated as a medical device in certain jurisdictions due to its mechanical mechanism of action, it is functionally a biologic polysaccharide in this therapeutic context.

Other names
hyaluronic acid + corticosteroidsodium hyaluronate + steroid
02

Targets

GR (Glucocorticoid receptor)

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