Drug intelligence / Profile preview

sodium hyaluronate + lidocaine (4269c9)

Development stage
Unknown
Lead developer
Haohai Healthcare Holdings
Modality
Small Molecules
Administration
Subcutaneous, Intradermal
01

Overview

Sodium hyaluronate + lidocaine is a cross-linked hyaluronic acid (HA) gel combined with lidocaine, developed by Haohai Healthcare Holdings for aesthetic soft tissue augmentation. The product functions as a dermal filler, where the sodium hyaluronate component acts as a volumizing scaffold within the extracellular matrix to correct wrinkles, folds, or volume loss. The inclusion of lidocaine, a local anesthetic, serves to block voltage-gated sodium channels, thereby reducing pain and discomfort associated with the injection process. Haohai markets these products under brands such as Matrifill and has developed multiple generations of the formulation, with approvals granted for aesthetic indications.

Brand names
Matrifill
Other names
cross-linked hyaluronic acid gel with lidocainesodium hyaluronate gel with lidocaine
02

Targets

SCN10A (Sodium channel protein type X alpha subunit)

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