Drug intelligence / Profile preview

sodium lactate + calcium chloride + magnesium chloride + sodium chloride + dextrose

Development stage
Approved
Lead developer
Vanttive
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

**Sodium lactate + calcium chloride + magnesium chloride + sodium chloride + dextrose** is a fixed-composition peritoneal dialysis solution used for intraperitoneal dialysis in renal failure. Dextrose creates an osmotic gradient across the peritoneal membrane to promote ultrafiltration and removal of excess fluid, while sodium lactate provides an alkali buffer that supports acid-base balance and the electrolyte salts replace or maintain dialysate sodium, calcium, magnesium, and chloride concentrations. Products with this active-ingredient set are marketed in multiple dextrose concentrations and electrolyte compositions, including Dianeal products from Vantive and Delflex products from Fresenius Medical Care.

Brand names
DianealDelflex
Other names
dextrose + sodium chloride + sodium lactate + calcium chloride + magnesium chloridedextrose peritoneal dialysis solution

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