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sodium lactate + calcium chloride + sodium chloride + magnesium chloride + dextrose
- Development stage
- Approved
- Lead developer
- Takeda
- Modality
- Small Molecules
- Administration
- Intraperitoneal
01
Overview
A sterile **peritoneal dialysis solution** containing **dextrose, sodium lactate, sodium chloride, calcium chloride, and magnesium chloride**, developed and marketed by **Baxter Healthcare** for intraperitoneal use in patients with renal failure. In this combination, **dextrose acts as the osmotic agent** that drives ultrafiltration across the peritoneal membrane, enabling removal of excess water and uremic solutes, while **sodium lactate serves as the buffer precursor** and the electrolytes help maintain physiologic ionic composition during dialysis. This product family is marketed under brands including **DELFLEX** and **DIANEAL** formulations and is indicated for **chronic kidney failure** in peritoneal dialysis patients and, for certain DIANEAL products, **acute or chronic renal failure**.
- Brand names
- DELFLEXDIANEAL Low CalciumDIANEAL PD-2
- Other names
- dextrose monohydrate + sodium chloride + sodium lactate + calcium chloride + magnesium chlorideperitoneal dialysis solution
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