Drug intelligence / Profile preview

sodium lactate + calcium chloride + sodium chloride + potassium chloride + dextrose

Development stage
Approved
Lead developer
Pfizer
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

Sodium lactate + calcium chloride + sodium chloride + potassium chloride + dextrose is a multi-ingredient intravenous crystalloid and carbohydrate solution marketed as Lactated Ringer's and Dextrose. It is an established hospital-use parenteral formulation used as a source of water, electrolytes, and calories and as an alkalinizing agent for replacement of extracellular fluid and electrolyte losses. Pharmacologically, its effect derives from physiologic electrolyte repletion, dextrose-mediated caloric support, and metabolism of lactate to bicarbonate, which can help buffer metabolic acidosis; it does not have a single discrete molecular target. The product has been manufactured by Hospira and is used in adults and pediatric patients in routine clinical care rather than as a targeted developmental asset.

Brand names
Lactated Ringer's and DextroseDextrose in Lactated Ringer's
Other names
lactated ringer's and dextrose injectionlactated ringer's and dextrose 5% injectionpotassium chloride in lactated ringer's and dextrose injectionpotassium chloride in lactated ringer's and dextrose 5% injectiondextrose in lactated ringer's

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