sodium lactate + calcium chloride + sodium chloride + potassium chloride + dextrose monohydrate

A sterile **intravenous crystalloid and dextrose combination solution** containing sodium lactate, calcium chloride, sodium chloride, potassium chloride, and dextrose monohydrate, used as a parenteral source of water, electrolytes, and calories and as an **alkalinizing agent**. The product is marketed as Lactated Ringer's and Dextrose Injection, including 5% dextrose formulations, and is manufactured by ICU Medical and marketed under labeling historically associated with Hospira and Pfizer. Its pharmacologic activity derives from replacement of extracellular fluid and electrolytes, provision of glucose calories via dextrose, and buffering of metabolic acidosis through hepatic conversion of lactate to bicarbonate; it does not have a single discrete molecular target and instead acts through restoration of **fluid balance, electrolyte homeostasis, acid-base balance, and caloric support** in adults and pediatric patients requiring intravenous replacement therapy.

Brand names

Lactated Ringer's and DextroseLactated Ringer's and Dextrose InjectionLactated Ringer's and Dextrose 5% Injection

Other names

lactated ringer's and dextroselactated ringer's and dextrose injectionlactated ringer's and dextrose 5% injectionpotassium chloride in lactated ringer's and dextrose 5% injectiondextrose hydrous + sodium chloride + sodium lactate + potassium chloride + calcium chloride dihydrate