sodium phosphate, dibasic + sodium phosphate, monobasic

**Sodium phosphate, dibasic + sodium phosphate, monobasic** is a combination oral or injectable drug comprised of sodium phosphate dibasic (disodium phosphate) and sodium phosphate monobasic (monosodium phosphate). It acts as an **osmotic laxative** by increasing fluid retention in the intestinal lumen, resulting in loose stools and subsequent bowel evacuation. The combination is primarily indicated for colon cleansing prior to colonoscopy in adults, and for the treatment or prevention of hypophosphatemia in patients who cannot receive oral phosphate supplements. As a phosphate replacement, it serves to restore low blood phosphorus. The mechanism involves drawing water into the intestines via osmotic effects of sodium ions, triggering diarrhea and effective bowel cleansing. It may also be administered intravenously as a phosphate additive in fluid preparations for patients with restricted oral intake[2][3][5][7].

Brand names

OsmoPrep

Other names

Monobasic Sodium Phosphate and Dibasic Sodium Phosphate Tabletssodium phosphate tablets