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Sodium phosphate monobasic monohydrate + sodium phosphate dibasic anhydrous

Development stage
Approved
Lead developer
Salix Pharmaceuticals
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

Sodium phosphate monobasic monohydrate + sodium phosphate dibasic anhydrous is a combination osmotic laxative used primarily for bowel cleansing prior to colonoscopy or other imaging procedures. The drug acts by drawing water into the colon through its osmotic effect, leading to diarrhea and effective evacuation of the bowel contents. This allows for improved visualization during diagnostic procedures. It is available in both oral tablet and intravenous forms; the oral form is used as a purgative for colon cleansing while the intravenous form serves as an electrolyte replenisher in clinical settings where phosphorus supplementation is required[1][3][4][5][7][8]. The mechanism of action involves increasing intraluminal fluid volume in the intestine via osmotic activity of phosphates.

Brand names
Fleet Phospho-soda EZ-PrepOsmoPrepPhospho-SodaVisicol
Other names
sodium phosphate dibasic and sodium phosphate monobasicmonobasic sodium phosphate and dibasic sodium phosphate tablets
02

Targets

CA4 (Carbonic anhydrase 4)

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