sodium sulfate + potassium sulfate + magnesium sulfate

Sodium sulfate + potassium sulfate + magnesium sulfate is a low-volume osmotic laxative combination used for colon cleansing in preparation for colonoscopy. The drug consists of poorly absorbed sulfate salts that create an osmotic gradient within the intestinal lumen, drawing water into the bowel to induce diarrhea and effectively evacuate fecal matter. It is typically administered as a split-dose or one-day regimen, where the concentrated solution is diluted with water and followed by additional clear liquids. Developed by Braintree Laboratories (now part of Sebela Pharmaceuticals) and licensed to partners like Ipsen and Nihon Pharmaceutical, it is approved for use in both adult and pediatric patients aged 12 years and older.

Brand names

SUPREP Bowel Prep KitEziclenIzinova

Other names

Oral sulfate solutionOSSMagnesium sodium potassium sulfate oral concentrated solution