Drug intelligence / Profile preview

sodium sulfate + potassium sulfate + magnesium sulfate (Taejoon Pharmaceutical Co., Ltd.)

Development stage
Phase 3
Lead developer
Taejoon Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Suclear is a brand name for a bowel preparation agent used as an osmotic laxative to cleanse the colon prior to colonoscopy. In the context of the South Korean market and clinical trials (e.g., NCT02551198), Suclear refers to an oral sulfate solution (OSS) composed of sodium sulfate, potassium sulfate, and magnesium sulfate. It works by creating an osmotic gradient that draws water into the intestinal lumen, thereby increasing stool volume and promoting evacuation. While the brand name Suclear was also used in the United States for a combination kit containing both an oral sulfate solution and a polyethylene glycol (PEG-3350) with electrolytes solution (developed by Braintree Laboratories and coded as BLI850), the Korean formulation marketed by Taejoon Pharm focuses on the sulfate solution. Clinical studies have demonstrated that the OSS formulation provides effective bowel cleansing with a lower volume of fluid compared to traditional 4L PEG solutions, often administered in a split-dose regimen.

Brand names
SuclearSuprep
Other names
Oral Sulfate SolutionOSS
02

Targets

CA1 (Carbonic anhydrase 1)CA2 (Carbonic Anhydrase 2)

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