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**Soybean oil + olive oil + fish oil + medium-chain triglycerides** is a four-component **intravenous lipid emulsion** used as part of **parenteral nutrition** to provide calories and essential fatty acids when oral or enteral feeding is not possible, insufficient, or contraindicated. Marketed as **SMOFlipid**, it contains a defined mixture of soybean oil, medium-chain triglycerides, olive oil, and fish oil, and is formulated to reduce omega-6 exposure while supplying monounsaturated fatty acids, omega-3 fatty acids, and vitamin E. Its therapeutic effect is nutritional rather than receptor-targeted: it replenishes lipid calories and essential fatty acids and helps maintain fatty acid balance in patients requiring intravenous nutrition, including adults, children, and term and preterm neonates. The product has been developed and commercialized for hospital parenteral nutrition use, with clinical experience particularly in neonatal, pediatric, and intensive care settings.
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