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stabilized chlorine dioxide + sodium fluoride
- Development stage
- Unknown
- Lead developer
- Rowpar Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Stabilized chlorine dioxide + sodium fluoride is a combination oral care formulation primarily used for the prevention of dental caries and the management of oral hygiene. Stabilized chlorine dioxide serves as an oxidizing agent that targets and disrupts oral biofilms, neutralizes volatile sulfur compounds (VSCs) responsible for halitosis, and exhibits broad-spectrum antimicrobial and antiviral properties. Sodium fluoride provides anticavity benefits by promoting the remineralization of tooth enamel and increasing its resistance to acid-driven demineralization. Developed by Rowpar Pharmaceuticals and marketed under the brand CloSYS, this combination is typically formulated as a toothpaste or oral rinse for topical application in the oral cavity.
- Brand names
- CloSYSCloSYS Anticavity Toothpaste
- Other names
- stabilized chlorine dioxide + fluoride
02
Targets
Polymicrobial oral dental biofilmHydroxyapatite
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