Drug intelligence / Profile preview

standard western medicine treatment + Chaigui Longmu Paste without Ejiao

Development stage
Unknown
Lead developer
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Standard western medicine treatment + Chaigui Longmu Paste without Ejiao is a combination therapy used as a control arm in clinical research conducted by Longhua Hospital for the treatment of ischemic heart disease (IHD). This intervention consists of conventional pharmacological treatments for IHD—typically including antiplatelet agents (e.g., aspirin), statins, and beta-blockers—combined with a modified Traditional Chinese Medicine (TCM) formulation. The TCM component, Chaigui Longmu Paste, is specifically prepared without Ejiao (donkey-hide gelatin) to serve as a parallel placebo comparator for the Ejiao-containing version (Chaigui Longmu Ejiao Paste). The TCM portion is likely based on the classical formula Chaihu Jia Longgu Mu Li Tang, which is traditionally used to soothe the liver, clear heat, and calm the spirit, addressing both physical and psychological symptoms associated with cardiovascular conditions.

Other names
Chaigui Longmu Paste without EjiaoStandard Western medicine treatment + Chaigui Longmu Paste without Ejiao
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)PGHS-1 (Prostaglandin G/H Synthase 1)ADRB1 (β1)

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