Drug intelligence / Profile preview

stannous fluoride + sodium fluoride

Development stage
Unknown
Lead developer
Procter & Gamble
Modality
Small Molecules
Administration
Topical
01

Overview

A combination of **stannous fluoride** and **sodium fluoride** is used in dental products such as toothpastes and mouthrinses to prevent dental caries, reduce gingivitis, decrease tooth sensitivity, and strengthen tooth enamel. Stannous fluoride provides **anticaries, antibacterial, and antisensitivity** effects by disrupting biofilm, reducing oral microbial viability, and forming a protective barrier over dentinal tubules. Sodium fluoride supplements the formulation with additional fluoride ions, aiding remineralization of enamel and further protecting against cavities. This combination leverages both stannous fluoride’s antimicrobial/antigingivitis properties and sodium fluoride’s established remineralizing effects, making it effective for comprehensive oral health management[1][2][3][4][5][7][8][9].

Brand names
Perfect ChoiceElmex EROSIONSSCHUTZPerioMedMeridol
Other names
tin difluoride + sodium fluorideSnF2 + NaF

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