Drug intelligence / Profile preview

stem cell secretome + liquorice root extract

Development stage
Unknown
Lead developer
ExoCoBio
Administration
Topical
01

Overview

The combination of **stem cell secretome** and **liquorice root extract** is a synergistic formulation primarily utilized in regenerative aesthetics and dermatology. The stem cell secretome, typically derived from human mesenchymal stem cells (MSCs) such as those from umbilical cord blood or adipose tissue, consists of a complex mixture of paracrine factors, including cytokines, chemokines, growth factors (such as EGF, FGF, and TGF-β), and extracellular vesicles (exosomes). These components promote tissue repair, stimulate collagen synthesis, and modulate inflammatory responses. Liquorice root extract (*Glycyrrhiza glabra*) contributes bioactive compounds like **glabridin** and **glycyrrhizin**, which provide potent antioxidant, anti-inflammatory, and skin-lightening effects through the inhibition of tyrosinase. This combination is frequently investigated for its efficacy in skin rejuvenation, wound healing, and the treatment of hyperpigmentation disorders such as melasma.

Other names
stem cell conditioned media + glycyrrhiza glabra extractMSC-CM + liquorice root extractmesenchymal stem cell secretome + licorice extract
02

Targets

VEGFR2 (Vascular endothelial growth factor receptor 2)TYR (Tyrosinase)

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