Drug intelligence / Profile preview

STK-012 + pembrolizumab

Development stage
Unknown
Lead developer
Synthekine
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration
Subcutaneous, Intravenous
01

Overview

STK-012 + pembrolizumab is a combination therapy being investigated for the treatment of advanced solid tumors. STK-012 is a modified form of interleukin-2 (IL-2), a cytokine normally produced by the immune system. It has been engineered in the laboratory to potentially activate the immune system to attack cancer cells. Pembrolizumab (KEYTRUDA) is an FDA-approved immune checkpoint inhibitor that may help turn on the immune system to attack cancer cells. The combination is being studied to determine the highest dose of STK-012 that can be safely given with a standard dose of pembrolizumab in patients with advanced solid tumors.

02

Targets

IL2RB (IL-2 receptor beta chain)PDCD1 (Programmed cell death protein 1 receptor)

Beyond the preview

Go deeper on STK-012 + pembrolizumab.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on STK-012 + pembrolizumab.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call