sufentanil + ropivacaine

Sufentanil + ropivacaine is a combination of a potent synthetic opioid analgesic and a long-acting amide-type local anesthetic. It is commonly used for epidural labor analgesia to provide effective pain relief during childbirth. Sufentanil acts as a highly selective agonist at the mu-opioid receptor, providing systemic and neuraxial analgesia. Ropivacaine works by reversibly blocking sodium channels in nerve fibers, inhibiting the conduction of nerve impulses. In clinical research conducted by Peking University First Hospital, this combination is often utilized as a standard of care comparator for evaluating novel analgesic regimens like dexmedetomidine-esketamine-ropivacaine.

Other names

sufentanil-ropivacaine combination