Sunscreen Lotion (FDA Absorption Study)

This sunscreen lotion refers to a specific topical formulation evaluated by the U.S. Food and Drug Administration (FDA) in a Phase 1 clinical trial (NCT03582215) to assess the systemic absorption and pharmacokinetics of active sunscreen ingredients. The lotion contains a combination of organic chemical UV filters, including avobenzone, oxybenzone, ecamsule, octocrylene, homosalate, octisalate, and octinoxate. These ingredients function by absorbing ultraviolet (UV) radiation, thereby preventing DNA damage in skin cells and protecting against sunburn and long-term skin damage. The study was initiated to determine if these active components are absorbed into the systemic circulation at levels that exceed safety thresholds established by the FDA, particularly when applied under maximal use conditions (multiple daily applications to a large percentage of the body surface area).

Other names

Sunscreen Lotion (FDA Absorption Study)lotion-Food and Drug Administration (FDA)-sunburn