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TAH9901 (methylphenidate)
- Development stage
- Preclinical
- Lead developer
- TAHO Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Transdermal
01
Overview
TAH9901 is a transdermal patch formulation of methylphenidate developed by Taihe Pharmaceutical for the treatment of pediatric Attention Deficit Hyperactivity Disorder (ADHD). As a central nervous system stimulant, it acts by inhibiting the reuptake of dopamine and norepinephrine through the blockade of the dopamine transporter (DAT) and norepinephrine transporter (NET), respectively. This inhibition leads to increased concentrations of these catecholamines in the synaptic cleft, enhancing neurotransmission in brain regions associated with attention and impulse control. The transdermal delivery system is designed to provide a controlled, sustained release of the medication, potentially offering improved patient compliance and a smoother pharmacokinetic profile compared to traditional oral formulations.
- Other names
- Methylphenidate Patch
02
Targets
DAT (Dopamine plasma membrane transport protein)NET (Norepinephrine Transporter)SERT (Sodium-dependent serotonin transporter)
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