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TAHP + AHP
- Development stage
- Phase 2
- Lead developer
- Roche
- Modality
- Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Administration
- Intravenous, Subcutaneous
01
Overview
TAHP + AHP is not a standard pharmaceutical product or recognized drug combination. Based on available clinical trial data, "TAHP" refers to a regimen used in the treatment of HER2-positive early breast cancer and typically includes trastuzumab (Herceptin), pertuzumab, and chemotherapy agents such as docetaxel and carboplatin. "AHP" in this context refers to an adjuvant phase that may include atezolizumab (an anti-PD-L1 antibody), Herceptin SC (subcutaneous trastuzumab), and pertuzumab[1]. The combination "TAHP + AHP" therefore appears to describe a sequential or combined therapeutic approach involving these agents for HER2-positive breast cancer patients, rather than a single drug entity.
- Other names
- TAHPAHP
02
Targets
ERBB2 (Erb-b2 receptor tyrosine kinase 2)CD274 (Programmed cell death protein 1 ligand 1)TUBB (Tubulin (alpha and beta subunits))
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