Drug intelligence / Profile preview

Talineuren (InnoMedica)

Development stage
Unknown
Lead developer
InnoMedica
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intravenous
01

Overview

Talineuren (TLN-1) is a liposomal formulation of GM1 ganglioside (monosialotetrahexosylganglioside) developed by InnoMedica. Utilizing a proprietary lipid nanoparticle technology platform, the drug is designed to cross the blood-brain barrier and improve the biodistribution of GM1, a glycosphingolipid naturally found in neuronal cell membranes. GM1 exhibits neuroprotective, neurorestorative, and neurotrophic properties by stabilizing cell membranes and modulating signaling pathways involved in neuronal survival. Talineuren is primarily being developed for neurodegenerative disorders, including Parkinson's disease and Amyotrophic Lateral Sclerosis (ALS), aiming to provide a more effective delivery mechanism and reduced treatment frequency compared to traditional GM1 administration.

Other names
GM1-GangliosideGM-1-GangliosideGM 1-Gangliosidemonosialotetrahexosylganglioside
02

Targets

GM1 (GM1 ganglioside)

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