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tamsulosin + dutasteride + nano-water
- Development stage
- Unknown
- Lead developer
- University of Sulaimani
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
tamsulosin + dutasteride + nano-water is a combination therapy being investigated for the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). The regimen consists of tamsulosin, an alpha-1 adrenergic receptor antagonist that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow; dutasteride, a 5-alpha reductase inhibitor that blocks the conversion of testosterone to dihydrotestosterone (DHT) to reduce prostate size; and nano-water (marketed as Magnalife), a dietary supplement hypothesized to enhance the clinical outcomes of the pharmacological treatment. This specific combination is the subject of a Phase 2 clinical trial led by investigator Ali Kamal M. Sami to determine if the addition of nano-water provides superior symptom relief compared to standard medication alone.
- Brand names
- Magnalife
- Other names
- Nano-water, Tamsulosin DutasterideNano-water with Tamsulosin-Dutasteridetamsulosin + dutasteride-ALI KAMAL M. SAMI
02
Targets
SRD5A2 (Steroid 5-alpha-reductase type II)ADRA1A (α1A)SRD5A1 (Steroid 5-alpha-reductase type 1)ADRA1D (α1D)ADRA1B (α1B)
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