Drug intelligence / Profile preview

Tears Again (Optima Pharma)

Development stage
Unknown
Lead developer
Optima Pharmazeutische
Modality
Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Ophthalmic, Topical
01

Overview

Tears Again is a liposomal eye spray developed by Optima Pharmaceutical GmbH, designed to treat dry eye disease by stabilizing the tear film's lipid layer. The formulation consists of phospholipid liposomes enriched with vitamins A and E, which are applied as a spray onto closed eyelids. Upon application, the liposomes migrate across the eyelid margins to integrate into the tear film, effectively mimicking the natural function of meibomian glands and reducing tear evaporation by up to 95%. It is particularly indicated for evaporative dry eye and tear film lipid deficiency, offering a preservative-free option compatible with contact lenses.

Brand names
Tears Again
Other names
Tears Again Liposomal Spray
02

Targets

Ocular surface lipid-aqueous/mucin interface

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