Drug intelligence / Profile preview

technetium (99mTc) macrosalb (Bracco Group)

Development stage
Unknown
Lead developer
Bristol Myers Squibb
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Gamma Emitters → Radiopharmaceuticals
Administration
Intravenous, Intraperitoneal
01

Overview

Technetium (99mTc) macrosalb (commonly referred to as technetium-99m albumin macroaggregates or Tc-99m MAA) is a diagnostic radiopharmaceutical used in nuclear medicine. It consists of human serum albumin that has been denatured and aggregated into particles of controlled size (typically 10 to 90 micrometers) and labeled with the gamma-emitting radionuclide technetium-99m. Upon intravenous injection, the macroaggregates are physically trapped by microembolization in the pulmonary capillary bed, allowing for the visualization of pulmonary perfusion via single-photon emission computed tomography (SPECT) or planar scintigraphy. It is primarily indicated for lung perfusion scintigraphy as an adjunct in the evaluation of pulmonary perfusion (e.g., for diagnosing pulmonary embolism) in both adult and pediatric patients. It is also used to evaluate the patency of peritoneovenous (LeVeen) shunts.

Brand names
DraxImage MAADraximage MacrosalbMPI MAAMacrotecPulmolitePulmotech MAATechnescan MAA
Other names
99mTc-MAATc 99m MAATc99m MAATc-99m MAATc-99m macroaggregated albuminTc99m macroaggregated albuminTc 99m macroaggregated albuminmacrosalb (99m Tc)technetium (99m Tc) macrosalbtechnetium (99mTc) albumin aggregatedtechnetium (99mTc) macrosalbtechnetium (99mTc) macrosalb injectiontechnetium Tc 99m albumin aggregatedtechnetium Tc 99m albumin aggregated injectiontechnetium Tc 99m albumin aggregated kittechnetium Tc 99m macroaggregated albumintechnetium-99m albumin macroaggregatestechnetium99m albumin macroaggregatestechnetium 99m albumin macroaggregatestechnetium-99m macroaggregated albumintechnetium99m macroaggregated albumintechnetium 99m macroaggregated albumin

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