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technetium tc-99m exametazime + cobaltous
- Development stage
- Unknown
- Lead developer
- General Electric
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
**Technetium tc-99m exametazime + cobaltous** is a diagnostic radiopharmaceutical kit formulation of technetium-99m labeled exametazime used for SPECT imaging. Exametazime, also known as HMPAO, is a lipophilic small-molecule chelator that complexes technetium Tc-99m and distributes in proportion to regional cerebral blood flow, enabling cerebral scintigraphy for detection of altered regional cerebral perfusion in stroke; in the Ceretec kit, cobaltous chloride is supplied as an optional stabilizer solution for cerebral imaging use. The product was developed and is manufactured by GE Healthcare and is administered intravenously with standard radiation-handling precautions. In the provided context, the cobalt-containing formulation is specific to cerebral scintigraphy rather than leukocyte labeling applications.
- Brand names
- Ceretec
- Other names
- technetium tc-99m exametazime + cobaltoustechnetium tc 99m exametazime + cobaltoustechnetium tc-99m exametazime with cobalt stabilizerexametazime + cobaltoushexamethylpropyleneamine oxime + cobaltousHMPAO + cobaltous
02
Targets
GSH (Glutathione)
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