Drug intelligence / Profile preview

telmisartan + hydrochlorothiazide

Development stage
Unknown
Lead developer
PharmaKing
Modality
Small Molecules
Administration
Oral
01

Overview

**Meijiasu** is an oral fixed-dose antihypertensive combination containing **telmisartan 80 mg** and **hydrochlorothiazide 12.5 mg** per tablet. Telmisartan is a selective angiotensin II type 1 receptor blocker that reduces angiotensin II-mediated vasoconstriction and aldosterone signaling, while hydrochlorothiazide is a thiazide diuretic that inhibits renal sodium-chloride reabsorption. The complementary mechanisms produce additive blood-pressure lowering and are used for adult primary hypertension inadequately controlled with telmisartan alone. Meijiasu is a Chinese brand of the telmisartan-hydrochlorothiazide product marketed internationally under MicardisPlus-related brand names by Boehringer Ingelheim.

Brand names
Co-MicardisMeijiasuMicardis HCTMicardis PlusMicardisPlus
Other names
telmisartan and hydrochlorothiazidetelmisartan hydrochlorothiazidetelmisartan/hydrochlorothiazide美嘉素
02

Targets

AGTR1 (Angiotensin II Type-1 receptor)SLC12A3 (Thiazide-sensitive sodium-chloride cotransporter)PPARG (Peroxisome proliferator-activated receptor gamma)

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