Drug intelligence / Profile preview

telmisartan + rosuvastatin

Development stage
Phase 4
Lead developer
Yuhan
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Telmisartan + rosuvastatin is a fixed-dose combination drug used to treat patients with both hypertension (high blood pressure) and hyperlipidemia (high cholesterol). It combines two active pharmaceutical ingredients: - **Telmisartan** is an angiotensin II receptor blocker (ARB) that lowers blood pressure by blocking the action of angiotensin II on its receptor. This leads to relaxation and widening of blood vessels. - **Rosuvastatin** is a statin (HMG-CoA reductase inhibitor) that reduces cholesterol levels by inhibiting the enzyme HMG-CoA reductase in the liver. This decreases production of "bad" LDL cholesterol and triglycerides while increasing "good" HDL cholesterol. The combination helps reduce cardiovascular risk in patients who require both antihypertensive and lipid-lowering therapy. It is available as an oral tablet for adult use[1][5][8].

Brand names
Tellzy-RST-Mart RRozution-TTelmidoz-RTelihep RSTelmirose RTTelroseBriztelTelosaf RVTelmade RS
Other names
telmisartan + rosuvastatin
02

Targets

AGTR1 (Angiotensin II Type-1 receptor)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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