Testosterone + anastrozole

Testosterone + anastrozole is a combination therapy involving the administration of exogenous testosterone (a naturally occurring androgen hormone) and anastrozole, a non-steroidal aromatase inhibitor. Testosterone is used to treat male hypogonadism and other conditions associated with low testosterone levels. Anastrozole inhibits the aromatase enzyme, which converts testosterone to estradiol (an estrogen), thereby reducing circulating estrogen levels. This combination is primarily used off-label in men undergoing testosterone replacement therapy (TRT) who develop elevated estradiol levels or symptoms of estrogen excess, such as gynecomastia or fluid retention. By inhibiting aromatization, anastrozole helps maintain a favorable testosterone-to-estradiol ratio and may improve hormonal balance, fertility parameters, and clinical outcomes in certain populations[2][3][5]. The use of this combination should be monitored by healthcare professionals due to potential side effects including changes in bone mineral density and cardiovascular risk[1][5].

Other names

testosterone plus anastrozoletestosterone/anastrozoleT+A