testosterone + dutasteride

Testosterone + dutasteride is a **combination drug** consisting of *testosterone*, an androgen and anabolic steroid, and *dutasteride*, a dual 5α-reductase inhibitor[1]. Testosterone acts primarily as a replacement therapy for male hypogonadism by supplementing deficient androgen levels, while dutasteride inhibits the conversion of testosterone to dihydrotestosterone (DHT), thereby reducing DHT-mediated effects such as prostate enlargement[1][2][4][6][8]. The combination was under development for the treatment of male hypogonadism, especially in men with benign prostatic hyperplasia (BPH), to provide androgen replacement while minimizing stimulation of the prostate gland by DHT[1][2][4][6][8]. This approach leverages the anabolic and androgenic effects of testosterone while using dutasteride to block local prostatic conversion to DHT to avoid or reduce adverse prostate effects[2][4][6]. Development was discontinued after phase II trials[1].

Other names

testosterone/dutasteride