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Drug intelligence / Profile preview
tetanus toxoid + diphtheria toxoid + inactivated poliovirus vaccine
- Development stage
- Phase 4
- Lead developer
- Parent
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
**Tetanus toxoid + diphtheria toxoid + inactivated poliovirus vaccine** is a combination vaccine that induces active immunity against tetanus (caused by *Clostridium tetani* toxin), diphtheria (caused by *Corynebacterium diphtheriae* toxin), and poliomyelitis (caused by poliovirus types 1, 2, and 3). It contains detoxified tetanus and diphtheria toxoids to stimulate antibody production neutralizing the respective toxins, alongside inactivated poliovirus antigens for humoral and mucosal immunity against polio. Primarily used as a booster in adolescents and adults for maintaining protection, especially in regions like the UK where it is administered around age 14; toxoids are adsorbed onto aluminum adjuvant for enhanced immunogenicity, with no pertussis component distinguishing it from DTaP-IPV vaccines.
- Brand names
- DT-IPV
- Other names
- DT + IPVTd/IPV
02
Targets
Diphtheria toxinPRR (Pattern recognition receptors)
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