Drug intelligence / Profile preview

Therapearl eye mask + Eyestil synfo

Development stage
Unknown
Lead developer
Bausch + Lomb
Modality
Small Molecules
Administration
Topical, Ophthalmic
01

Overview

The combination of the Therapearl eye mask and Eyestil synfo eye drops constitutes a home-based therapeutic regimen used for the management of meibomian gland dysfunction (MGD) and evaporative dry eye disease. The Therapearl eye mask (Bausch & Lomb) is a medical device that utilizes heat therapy to soften and liquefy thickened meibum within the meibomian glands, facilitating its expression and improving the lipid layer of the tear film. Eyestil synfo (Sifi) is a hypotonic ophthalmic solution containing sodium hyaluronate and xanthan gum. It acts as a lubricant and mucomimetic to stabilize the tear film, reduce evaporation, and protect the ocular surface from hyperosmolarity-induced damage. This specific combination was evaluated by the University of Seville as a standard-of-care control and adjunctive therapy in clinical trials investigating advanced procedural interventions for dry eye.

Brand names
TherapearlEyestil synfo
Other names
Home-based therapy-University of Seville-dry eye disease-meibomian gland dysfunctionHome-based therapy
02

Targets

CD44 (CD44 antigen)

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